NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which statement is true about the handling of Anti-TNF Biologic DMARDs?

  1. They should be shaken before use

  2. They can be frozen for long term storage

  3. Requires refrigeration

  4. All of the above

The correct answer is: Requires refrigeration

Anti-TNF Biologic DMARDs, such as adalimumab and etanercept, are sensitive to temperature and light. They should be stored in the refrigerator at a specific temperature range to maintain their stability and efficacy. Therefore, the statement that Anti-TNF Biologic DMARDs require refrigeration is true. Options A and B are incorrect because shaking these medications before use or freezing them for long-term storage can compromise their effectiveness and stability.

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