NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which treatment is not recommended for latent tuberculosis in pregnant patients?

  1. INH + Rifapentine

  2. INC + Rifampin

  3. Rifampin only

  4. INH only

The correct answer is: INH + Rifapentine

While rifampin is not recommended as the only treatment for latent tuberculosis in pregnant patients, it can be used in combination with other drugs such as INH or rifapentine. INH + Rifapentine is also not recommended as it carries a higher risk of hepatoxicity compared to other combinations such as INH + Rifampin. Additionally, INH + Rifapentine is not safe to use during pregnancy as rifapentine is a more potent form of rifampin and may increase the risk of adverse effects in the mother and fetus. Therefore, the safest treatment option for latent tuberculosis in pregnant patients is Rifampin only.

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