NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Ace your North American Pharmacist Licensure Examination (NAPLEX) with our comprehensive practice test. Features include interactive flashcards, multiple-choice questions, with detailed hints and explanations. Fast-track your pharmacy career today!

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Which type of antibiotic is known for having a small volume of distribution (Vd)?

  1. Lipophilic antibiotics

  2. Hydrophilic antibiotics

  3. Beta-lactams

  4. Macrolides

The correct answer is: Hydrophilic antibiotics

Hydrophilic antibiotics are known for having a small volume of distribution (Vd) because they are water-soluble and can distribute evenly throughout the body, resulting in a lower concentration in the tissues. Lipophilic antibiotics, on the other hand, are fat-soluble and can accumulate in fatty tissues, resulting in a higher Vd. Beta-lactams and macrolides are both types of antibiotics, but they are not specifically known for having a small Vd. Therefore, they are incorrect choices for this question.