NAPLEX (North American Pharmacist Licensure Examination) Practice Exam

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Which type of drugs can worsen BPH?

  1. ACE inhibitors

  2. Beta blockers

  3. Centrally acting anticholinergics

  4. Nitrates

The correct answer is: Centrally acting anticholinergics

Centrally acting anticholinergics can worsen Benign Prostatic Hyperplasia (BPH) symptoms by causing urinary retention and obstruction. These drugs have anticholinergic effects that can lead to smooth muscle contraction in the bladder neck and prostate, resulting in increased difficulty in urination and worsening of BPH symptoms. Therefore, the correct answer is C. ACE inhibitors, beta blockers, and nitrates are not typically associated with worsening BPH symptoms.

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